Glucagon相关论文
Glucagon is a potent glucose-elevating hormone that is secreted by pancreatic α- cells. While well-controlled glucagon ......
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The histological structure of the liver and pancreas and distribution of glucagon of pancreas in the
Glucagon is the hyperglycemic factor that opposes the action of insulin.It stimulates the breakdown of liver glycogen an......
A new method to evaluate the mass and the function ratio of alpha cells versus beta cells during T2D
Pancreatic islets are the main organ to maintain glucose homeostasis by beta cells of which secreting insulin and alpha ......
Glycated haemoglobin reduction and fixed ratio combinations of analogue basal insulin and glucagon-l
BACKGROUND Fixed ratio combinations(FRCs)of analogue basal insulin and glucagon-like peptide-1 receptor agonists are a n......
Influence of glucagon-like peptide 1 on the expression of ACAT1,CD36 gene and cholesterol metabolism
Objective:To investigate whether glucagon like peptide-1(GLP-1)can reduce the cholesterol in foam cells derived from mac......
Effects of Glucagon-Like Peptide 1 on PDX-1, PAX-6 and NKx2.2 Gene Expressions in Isolated Pancreati
Objective: To observe the effect of glucagon-like peptide 1(GLP-1) on the gene expressions of transcription factors (PDX......
Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflam
Glucagon-like peptide1(GLP-1)is secreted from Langerhans cells in response to oral nutrient intake.Glucagon-like peptide......
The enzyme, dipeptidyl peptidase Ⅳ(DPP Ⅳ), is a novel target for the treatment of type 2 diabetes. Dipeptidyl peptidas......
AIM: To observe the protective effect of glucagon-like peptide-2(GLP-2) on the intestinal barrier of rats with obstructi......
Pathophysiological mechanisms involved in non-alcoholic steatohepatitis and novel potential therapeu
Non-alcoholic fatty liver disease(NAFLD) is a major health care problem and represents the hepatic expression of the met......
在应用实时荧光定量PCR法观察胰岛素(In)、胰高血糖素(GLN)、神经肽(NPY)对体外培养新生犊牛肝细胞硬脂酰CoA去饱和酶(Stearoyl CoA desat......
<正> Glucagon is a polypeptide hormone of 29 amino acids which is synthesized by the α-cell of the islets of Langerhans......
如所周知,关于烧伤后蛋白质分解代谢的机理已有过广乏地研究,但是对于这些反应的精确的激素调节问题迄今未予阐明。已发现在一些......
糖尿病患者因胰岛素所致低血糖反应的治疗通常是口服糖、静脉注射葡萄糖或肌内、皮下注射胰升糖素(glucagon)。但病人昏迷、躁动......
β-阻断剂广泛的临床应用,也带来了药源性疾病;一旦过量可出现下列中毒症状:心衰、低血压、心率与传导减慢和支气管痉挛等。习惯......
胰高糖素(glucagon)由胰岛A细胞所分泌,并刺激B细胞及D细胞使之分别分泌胰岛素及生长激素释放抑制因子。在正常情况下,胰高糖素与......
AIM:To investigate the mechanism behind β-cell regeneration in neonatal rat pancreas treated with streptozotocin (STZ).......
Thirteen thiomorpholine-bearing compounds were designed and synthesized as dipeptidyl peptidase IV(DPP-IV) inhibitors, w......
[Objective] To study the effects of Zishen Qinggan( Shuangyi) Prescription on blood glucose,Hb A1c( glycosylated hemoglo......
The hormone-secreting endocrine cells(α,β,δ,ε and PP cells)form pancreatic islets,which are strongly involved in reg......
Type 2 diabetes mellitus is emerging as a new clinical problem within pediatric practice.Recent reports indicate an incr......
Influence of acute hyperglycemia in human sepsis on inflammatory cytokine and counterregulatory horm
AIM:In human sepsis,a prominent component of thehypermetabolite is impaired glucose tolerance (IGT) andhyperglycemia.El......
Dipeptidyl peptidase Ⅳ(DPP4) inhibitors are proven in the treatment of type 2 diabetes.We designed and synthesized a se......
胰高血糖素样肽-1(glucagon-like peptide- 1,GLP-1)是一种由小肠L-细胞分泌的多肽激素。GLP-1能够在高血糖水平下促进胰岛素分泌......
Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-pr
Bckground Stem cells,which have the ability to differentiate into insulin-producing cells (IPCs),would provide apotenti......
Efficacy and safety of vildagliptin/pioglitazone combination therapy in Korean patients with diabete
AIM:To assess the efficacy and safety of vildagliptin/pioglitazone combination therapy in Korean patients with type 2 di......
The addition of the dipeptidyl peptidase-4 (DDP-4) inhibitor has been reported to achieve greater improvements in glucos......
AIM:To evaluate the efficacy and safety of the addition of vildagliptin to low-dose metformin and compare it to an uptit......
John Murtagh著作在中国也产生了巨大的影响,目前,《Murtagh′s General Practice》中译本正在翻译出版中,将于2010年4月面世。“......
AIM: To investigate the effect of proton pump inhibitors (PPIs) on glycemic control (HbA1c) in type 2 diabetic patients.......
Regenerative medicine,including cell-replacement strategies,may have an important role in the treatment of type 1 diabet......
Hypercalcemia Appeared in a Patient with Glucagonoma Treated with Octreotide Acetate Long-acting Rel
PABCREATIC neuroen docrine tumours are uncom-mon neoplasms of the pancreas.They may causea clinical syndrome due to horm......
Pharmacological inhibition of diacylglycerol acyltransferase-1 and insights into postprandial gut pe
AIM To examine the role that enzyme Acyl-CoA:diacylglycerol acyltransferase-1(DGAT1) plays in postprandial gut peptide s......
目的探讨2型糖尿病患者胰高血糖素样肽-1(glucagon-like peptical-1,GLP-1)水平与血糖、胰岛素及胰岛素抵抗的关系。方法 2型糖尿......
应用胰高血糖素样肽-1(glucagon-like peptide-1,GLP-1)及其类似物治疗2型糖尿病是代谢性疾病研究领域近年来的热点,尤其是胰高血......
AIM:To investigate whether uncoupling protein 2(UCP2) affects oleic acid-induced secretion of glucagonlike peptide-1(GLP......
Role of glucagon-like peptide-1 analogue liraglutide played in the proliferation of CD4~+ CD25~- T c
Objective To study the role of glucagon-like peptide-1 (GLP-1) analogue liraglutide played in the proliferation of CD4+C......
Glucagon-like peptide-1(GLP-1)receptor agonists result in greater improvements in glycemic control than placebo and prom......
AIM: To assess the effects of sitagliptin and nateglinide on lipid metabolism. METHODS: In a parallel group comparative ......
目的探讨代谢手术(metabolic surgery)对肥胖合并2型糖尿病患者血管舒张功能(vascular dilation)的影响及发生机制。方法 105例健......
胰高血糖素样肽-1(glucagon-like peptide-1,GLP-1)是肠道L细胞分泌的一种重要的肠促胰岛素.大量研究表明,除刺激胰岛素分泌外,GLP......
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Relationship between islet α-cell function and glomerular filtration rate in type 2 diabetic patient
Objective To analyze the isletα-cell function in type 2 diabetic patients with different levels of glomerular filtratio......
胰高血糖素样肽-1(glucagon-like peptide-1,GLP-1)是一种重要的肠促胰素,除了血糖控制作用外,近年来大量研究证实它还能增加胰岛......
AIM: To identify the glucose lowering ability and chronic treatment effects of a novel coumarin-glucagon-like peptide-1(......
FDA批准改善血糖控制的阿比鲁泰(albiglutide)皮下注射剂,同时配合饮食和运动调节,用于成人2型糖尿病的治疗。阿比鲁泰是高血糖素......